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admetcove200x274ADMET and DMPK


Editor-in-chief: Kin Tam

jesecover193x273Journal of electrochemical science and engineering


Editor-in-chief: Višnja Horvat-Radošević





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Physico-Chemical Methods in Drug Discovery and Development

Editor: Zoran Mandić


  • Impressum

  • Content

  • Preface

Published by: IAPC Publishing, Zagreb, Croatia, 2012

Editor: Zoran Mandić

Title: Physico-Chemical Methods in Drug Discovery and Development

Copyright © 2012, IAPC. All rights reserved.

No part of this book may be reproduced in any form or by any means without written permission from the publisher. No part of this book may be transmitted or translated into a machine or other languages.

The efforts have been made to publish reliable and accurate data as much as possible, but the authors the editor cannot assume responsibility for the validity of materials or the consequences of their use.


ISBN 978-953-56942-0-5

Printed in Zagreb, Croatia, IAPC Publishing is a part of the International Association of Physical Chemists

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Chapter 1. Physicochemical Profiling in Drug Research and Development
Krisztina Takács-Novák

Chapter 2. Application of High Performance Liquid Chromatography for the Measurements of Lipophilicity and Biomimetic Binding Properties in Drug Discovery
Klara Valko

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Improving human health and preventing illness and various diseases is one of the major areas of human endeavour in contemporary science. Huge amounts of money are invested in drug research both in academic institutions and pharmaceutical companies. Discovery of new biologically active chemical entities, their promotion in clinical candidates and drug molecules, as well as design of efficient drug formulations and their improvement are long-term tasks requiring a multi-disciplinary approach. Throughout the research process scientists are faced with challenges where important decisions have to be made and crucial actions have to be taken in order to keep pace with ever-increasing demands from the pharmaceutical market and pharmaceutical management.

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