Program and Sessions

The whole scientific program will take place in the Hotel Westin, Izidora Kršnjavoga 1, 17th floor. 

 Download the Poster session program

Sunday, September 03rd

15:00 – 19:30
Participant registration

20:00 –
Welcome party (Museum of Arts and Crafts, Trg maršala Tita 10)

Monday, September 04th

08:00 – 09:00
Poster mounting

09:00 – 09:15
Opening ceremony

 
Drug development session (Moderators: Biserka Cetina Čižmek, Christos Reppas)
09:15 – 10:00
Christos Reppas, University of Athens, Greece
The environment in the lower intestine and its impact on drug absorption

10:00 – 10:45
Abu Serajuddin, St. John's University, USA
Strategies for the development of liquid, semisolid and solid lipid-based drug delivery systems

10:45 – 11:00
Coffee break
11:00 – 11:40
Mario Jug, Anita Hafner, Jasmina Lovrić, Maja Lusina Kregar, Ivan Pepić, Željka Vanić, Biserka Cetina-Čižmek, Jelena Filipović-Grčić, University of Zagreb, Croatia
In vitro dissolution/release methods for novel mucosal drug delivery systems

11:40 – 12:10
Seval Korkmaz, Biruni University, Turkey
How to increase the success of bioequivalnece studies in the generic drug industry?

12:10 – 12:35
Imre Dékány, Edit Csapóa, Hajnalka Szokolai, Ádám Juhásza, Ágota Deák, László Janovák, University of Szeged, Hungary
Design of colloidal drug delivery systems for controlled release of non-steroidal anti-inflammatory drugs

12:35 – 13:00
Marieta Duvnjak Romić, Drago Špoljarić, Biserka Cetina-Čižmek, Jelena Filipović-Grčić and Anita Hafner, PLIVA, Croatia
Spray-dried melatonin-NLC loaded chitosan microspheres: development, optimisation and physicochemical characterization
  Lunch
 

Solid state session
(Moderator: Rolf Hilfiker)

15:00 – 15:45
Wei Gao, Tonglei Li, Purdue University, USA
Exploring In Vivo Fate of Drug Nanocrystals

15:45 – 16:30
Elena Boldyreva, Novosibirsk State University, Russia
Drugs as materials: processing, structure, properties

16:30 – 16:45
Coffee break
 

Cocrystal session
(Moderator: Alex Avdeef), PDF

16:45 – 17:45

Nair Rodriguez-Hornedo, University of Michigan, USA
Cocrystal thermodynamic and kinetic properties: Mathematical relationships and insights

17:45 – 18:30
Rafel Prohens, University of Barcelona, Spain
Application of Surface Site Interaction Points calculation to cocrystal screening

18:30 – 19:15
Rolf Hilfiker, Solvias AG, Switzerland
Co-Crystals: The role of phase diagrams in optimizing experimental strategies

 
Short break
20:15 – 21:00
Nikoletta Fotaki, University of Bath, UK
Dissolution of pharmaceutical cocrystals for oral administration

21:00 – 21:45
Abu Serajuddin, St. John's University, USA
How Feasible is it to Form Cocrystals by Acid-base Interaction?

21:45– 22:30
Alex Avdeef, In-ADME Research, USA
Cocrystal Dissolution-pH Mechanistic Models: Aqueous Boundary Layer Convection-Diffusion-Reaction in Rotating Disk/Powder Methods

22:30
Cocrystal session closing remarks

Tuesday, September 05th

 
Physchem, permeability and instrumental session (Moderator: Marti Roses)
09:00 – 09:40
Klara Valko, Biomimeic chromatography, UK
How to optimize the physicochemical and biomimetic properties of putative drug molecules?

09:40 – 10:15
Shenaz Bunally, GSK, UK
Industrialisation of physicochemical measurements in early drug discovery

10:15 – 10:50
Marina Shalaeva, Pfizer, USA
Phys chem tool box for drug design in Beyond rule of Five chemical space

10:50 – 11:05
Coffee break
 
Moderator: Kin Tam

11:05 – 11:50
Annette Bauer-Brandl, University of Southern Denmark, Denmark
A new approach for HT permeability screening based on a biomimetic barrier

11:50 – 12:35
Kiyohiko Sugano, Ritsumeikan University, Japan
A mechanistic intestinal cell permeation model

12:35 – 13:00
Mare Oja, Uko Maran, University of Tartu, Estonia
Measuring, modelling and predicting pH-profiles of membrane permeability

  Lunch
  Moderator: Kiyohiko Sugano

15:00 – 15:40
Martí Rosés, Clara Ràfols, Elisabet Fuguet, Xavier Subirats and Susana Amézqueta, University of Barcelona, Spain
Surrogation of ADMET processes by chromatography and capillary electrophoresis

15:40 – 16:20
John Comer, Sirius Analytical Ltd, UK
Behaviour of ionisable drugs after precipitation from aqueous solution in response to pH change

16:20 – 16:40
Theodoros Avgerinos, Nikolaos Kantiranis, Kyriakos Kachrimanis, Ioannis Nikolakakis, Aristotle University of Thessaloniki, Greece
Mechanical properties of Venlafaxine HCl solid mini matrices prepared by hot-melt extrusion and hot or ambient compression and effect of plasticizer

16:40 – 17:00
Coffee break
 
Moderator: Klara Valko

17:00 – 17:40
M. Abrami, G. Chiarappa, R. Farra, G. Grassi, P. Marizza, M. Grassi, University of Trieste, Italy
Use of Low field NMR for the characterisation of gels and biological tissues

17:40 – 18:20
Gesa Schad, Shimadzu Europa GmbH, Germany
Automated LC and SFC method development for new APIs: The power of selectivity and the strength to choose

18:20 – 18:50
Olivera S. Marković, Jelena M. Konstantinović, Ilija N. Cvijetić, Susana Amézqueta, Klara Valko, Clara Ràfols, Natalija Đ. Polović, Bogdan A. Šolaja, Tatjana Ž. Verbić, University of Belgrade, Serbia
Measurements of plasma protein binding – variety of experimental techniques

18:50 – 23:00
Poster session

Wednesday, September 06th

08:00 – 09:00
Poster dismounting

 
ADMET and DMPK session (Moderator: Tatjana Verbić)
09:00 – 09:45
Godefridus J Peters, Anne-Sophie Govaerts, Hans R Hendriks, VU University Medical Center, The Netherlands
The role of pharmacology in European cancer drug development

09:45 – 10:30
Susanne Winiwarter, AstraZeneca R&D, Sweden
Simulation of in vitro Caco-2 Papp from Molecular Structure (Kubinyi vs. QSAR) and Estimation of Intracellular Km for Efflux Transporters

10:30 – 10:50
Ana Bokulić, Astrid Milić, Jasna Padovan, Fidelta d.o.o. Croatia
Automation of ADME in vitro binding assays using HTDialysis device on Tecan Freedom EVO
10:50 – 11:20
Coffee break
 

Drug discovery session
(Moderator: Godefridus Peters)

11:00 – 11:35

Bin Li, Peng Lyu, Rui Ma, Ravikiran Mahadevappa, Xinping Xi, Hang Fai Kwok, University of Macau, Macau
Venom-based Peptide Drug Discovery: Enhancing Specificity in Cancer Treatment

11:35 – 12:10
Shao-Lin Zhang, Zheng Yang, Kin Yip Tam, University of Macau, Macau
4-Isopropyl-3-nitro-dichloroacetophenone (INDAP) targets pyruvate dehydrogenase kinase 1 and inhibits cancer cells proliferation
  Conference closing
16:30 Organized sightseeng of Zagreb
20:00 Conference dinner

Thursday, September 07th

09:00 – 18:00 Optional excursion to the Plitvice lakes national park

 

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