Program

Download the list of poster presentations
 
Sunday, September 22nd
09:00 – 10:00
Participant registration, Conference Hall, Hotel Princess Royal
10:00 – 12:00 &
16:00 – 18:00
Course 1, Lecture Room “Neptun”, Hotel Neptun
QSAR analysis - principles, methods and applications, Stefan Dove, University of Regensburg, Germany 
10:00 – 12:00 &
16:00 – 18:00
Course 3, Lecture Room “Lokrum”, Hotel Neptun
ABC of Modelling Transporter Data - Principles and Practical Know How, Sibylle Neuhoff, Simcyp Ltd, UK
15:00 – 19.30
Participant registration, Conference Hall, Hotel Princess Royal
20:00 -
Welcome party, Taraca Lounge bar
 
Monday, September 23rd  (Royal Banquet Hall, Hotel Princess Royal)
 
08:00
Poster mounting, Princess Room 1, In front of the Royal Banquet Hall
09:00
Opening Ceremony
 
Chairs: Biserka Cetina Čižmek and John Comer
09:15
Alan Hill, GSK, UK, Physico-chemical profiling for Successful Lead Optimisation: Minimising the Risk of Attrition
09:55
Paul J. Russell, Unilever, UK, The role of physicochemical properties in pathways based toxicology risk assessment
10:30
Vesna Gabelica Marković, Fidelta Ltd, Croatia, Integrated physico chemical methods for effective drug candidate selection
10:45
Coffee break
11:00
Kin Tam, Gergely Völgyi, Gábor Vizserálek, Krisztina Takács-Novák, Alex Avdeef, University of Macau, China, Uses of physicochemical properties to estimate the pharmacokinetics and pharmacodynamics of antibacterial fluoroquinolones
11:40
Martí Rosés, Joan Marc Cabot, Elisabet Fuguet, Xavier Subirats, Universitat de Barcelona, Spain, High throughput determination log Po/w/pKa/log Do/w of drugs by combination of UHPLC and CE methods
12:20
Konstantin Tsinman, Oksana Tsinman, Alex Avdeef, in-ADME Research, USA, Applications of in situ Concentration Monitoring: Release from Nanoparticles, Supersaturation, Dual Component Separation and more …
13:00
Lunch
 
Chairs: Alex Avdeef and Kin Tam
15:00
John Comer, Sirius Analytical Ltd., UK, The importance of pKa values in pharmaceutical science
15:40
Robert Fraczkiewicz, Robert D. Clark, Alexander Hillisch, Andreas H. Göller, Ursula Krenz, Rolf Schoenneis, Mario Lobell, Simulations Plus, USA & Bayer, Germany, The absolute importance of applicability domain in QSAR: A new in silico multiprotic pKa prediction tool with significantly improved prediction accuracy and new functionality for PhysChem, MedChem, CompChem, and Cheminformatics applications
16:20
Igor V. Tetko,Sergey Novotarskyi, Iurii Sushko, Robert Körner, Ahmed Abdelaziz, Helmholtz Zentrum München - German Research Center for Environmental Health, Germany, On-line Chemical Modelling Environment – database and models for physico-chemical properties
17:00
Coffee break
17:20
Stefan Dove, Universtiy of Regensburg, Germany, Multivariate analysis of hydrophobic parameters
17:50
Christos Reppas, National and Kapodistrian Collaborators of Athens, Greece, Biorelevant in vitro performance testing of orally administered drug products: What and Why
18:20
Seval Korkmaz, Abdi Ibrahim, Turkey, Usage of Caco-2 Permeability Studies for Biowaiving and Bioequivalence Applications of Immediate Released Generic Drug Formulations
18:50
Rameshwar K. Deshmukh, Jitendra B. Naik, University Institute of Chemical Technolgy, India, Aceclofenac microspheres: Optimization of formulation using IV-Optimal statistical Design
19:20
End of Monday's session
     
 
Tuesday, September 24th   (Royal Banquet Hall, Hotel Princess Royal)
 
Chairs: Rolf Hilfiker and Mario Grassi
09:00
Alex Avdeef, in-ADME Research, USA, Salt Solubility Determination, Complicated by the Presence of Drug Aggregates, Drug-Buffer Precipitates, and Co-precipitated Solids
09:40
Jörg Berghausen, Novartis Institutes for Biomedical Research, Switzerland, Diagnosing solubility limitations – the example of hydrate formation
10:15
Z. Wojnarowska, K. Grzybowska, L. Hawelek, M. Dulski, M. Paluch, K.J. Paluch, L. Tajber, W. Sawicki, University of Silesia, Poland, Molecular Dynamics, Physical Stability and Solubility Advantage from Amorphous Indapamide Drug
10:45
Coffee break
11:05
Ulrich Griesser, Doris E. Braun, University of Innsbruck, Austria, High-throughput gravimetric moisture sorption in pharmaceutical preformulation
11:45
Jan Smith, Synthon BV, The Netherlands, DVS: Application within a generic pharmaceutical company
12:20
Simona Cîntă Pînzaru, C. A. Dehelean, A. Fălămas, M. Steiner, Babes-Bolyai University, Romania, Advanced Raman techniques in new drugs research and development
13:00
Lunch
 
Chairs: Ulrich Griesser
15:00
Rolf Hilfiker, Solvias AG, Switzerland, Co-Crystals: A tool to fine-tune solid-state properties
15:40
M. Grassi, A Piccolo, M. Abrami, S. Fiorentino, R. Farra, G. Grassi, D. Hasa, D. Voinovich, B. Perissutti, I. Colombo, Trieste University, Italy, Determination of nanocrystals size distribution in polymer-drug systems
16:20
Coffee break
16:40
Elena Boldyreva, Novosibirsk State University, Russia, Mechanochemistry of drugs
17:20
Jindřich Hašek, Institute of Biotechnology, Czech Republic, X-ray diffraction methods in drug design
17:55
M. Paluch, K. Grzybowska, K. Kołodziejczyk, A. Grzybowski, Z. Wojnarowska, L. Hawelek, J. D. Zioło, University of Silesia, Poland, Relaxation dynamics and crystallization study of sildenafil in the liquid and glassy states
18.30
Poster session (until 23:00)
 
 Wednesday, September 25th (Royal Banquet Hall, Hotel Princess Royal)
08:00
Poster dismounting
 
Chairs: Vesna Gabelica Marković and Predrag Novak
09:00
Sibylle Neuhoff, Simcyp (a Certara company), UK, In vitro - in vivo extrapolation of transporters
09:40
Michael Przybylski, University of Konstanz, Germany, Affinity- Mass Spectrometry and Ion Mobility- Mass Spectrometry: New Tools for elucidating structures, reaction pathways and interactions of “misfolding” - aggregating proteins
10:20
Tamás Sovány, Ildikó Oláh, Péter Kása jr., Klára Pintye-Hódi, University of Szeged, Hungary, Application of PAT methods in the development and quality control of Orally Disintegrating Tablets
10:50
Coffee break
11:10
Geoff Holdgte, AstraZeneca, UK, Fragment-Based Lead Generation in Drug Discovery
11:50
Dégardin Klara, Roggo Yves, Margot Pierre, F. Hoffmann-La Roche, Switzerland, Forensic Intelligence for Medicine Anti-Counterfeiting
12:30
Lunch
14:00
Excursion + Social Dinner
 

Thursday, September 26th, Joint PCMDDD-3 & COST Action TD 1002 session (Lecture room Coral, Hotel Neptun)

 
Chairs: Vesna Svetličić and Pierre Parot
09:00
Ratnesh Lal, Srinivasan Ramachandran, Fernando Teran Arce, Preston Landon, University of California San Diego, USA, AFM Nanoimaging and nanomechanics for nanomedicine,
09:40
Robert Henderson, University of Cambridge, UK, G-quadruplex DNA and DNA origami: Insights from atomic force microscopy
10:20
Coffee break
10:35
Jean-Luc Pellequer, Shu-wen W. Chen, Michael Odorico, Jean-Marie Teulon, Pierre Parot, Rui C. Chaves, CEA, France, Structural dynamics of single molecules using Atomic Force Microscopy
11:15
 
Seminar/Workshop
Michael Przybylski, Stefan Slamnoiu, Mihaela Stumbaum, Camelia Vlad, Kathrin Lindner, Christiaan Karreman, Marcel Leist, and Bastian Hengerer, University of Konstanz, Germany, Online Bioaffinity-Mass Spectrometry: New Tool for Simultaneous Detection, Structure Determination and Affinity Quantification of Protein-Ligand Interactions from Biological Material
12:00
Conference closing
 
 
 

 

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